WebbA series of 5′-phosphorylated (dialkyl phosphates, diaryl phosphates, phosphoramidates, H-phosphonates, phosphates) 1,2,3-triazolyl nucleoside analogues in which the 1,2,3-triazole-4-yl-β-D-ribofuranose fragment is attached via a methylene group or a butylene chain to the N-1 atom of the heterocycle moiety (uracil or … Webb1 maj 2013 · Based on the character of the molecular structure, the prodrugs of phosphates and phosphonates were divided into two categories. The first is the drug which contained the phosphate group, introducing protected groups to increase lipophilicity and improve bioavailability.
Prodrugs of phosphates and phosphonates: Novel lipophilic alpha ...
WebbMentioning: 3 - Prodrugs of phosphates and phosphonates: Novel lipophilic α-acyloxyalkyl ester derivatives of phosphate- or phosphonate containing drugs masking the negative … WebbPhosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects Marcela Krečmerová, Pavel Majer, Rana Rais, Barbara S. Slusher; … tcdsb pa days 2022
Medicinal Chemistry of Phosphonate - Cardiff University
Webbför 2 dagar sedan · Phosphonates, in particular, can be regarded as isosteres of the corresponding phosphate esters and serve as phosphate mimics in biochemical … Webb31 jan. 2008 · The article focuses on the topic(s): Prodrug & Deoxyribonucleotide. Menu. Log in Sign up. Overview Citations (365) References (158) Home / Papers / Prodrugs of … Webb1 feb. 2008 · Prodrugs of Phosphates and Phosphonates - Journal of Medicinal Chemistry (ACS Publications) Prodrugs of Phosphates and Phosphonates ADVERTISEMENT Log In … tcdsb pa days 2021