WitrynaBut with the emergence of single-cell applications, researchers can now estimate the metabolic state of individual immune cells in clinical samples. Here, we review these single-cell techniques and their ability to validate common principles in immunometabolism, while also revealing context-dependent metabolic … WitrynaBut with the emergence of single-cell applications, researchers can now estimate the metabolic state of individual immune cells in clinical samples. Here, we review these single-cell techniques and their ability to validate common principles in immunometabolism, while also revealing context-dependent metabolic …
Measuring Metabolism Across Scales - Chan Zuckerberg Initiative
Witryna13 kwi 2024 · The Chan Zuckerberg Initiative (CZI) seeks to support two-year collaborative research projects focused on measuring metabolism across organelles and cells. The ability to characterize temporally and spatially the broad molecular profiles, heterogeneity, and phenotypic diversity of organelles and cells and how they interact … WitrynaMaternal obesity is associated with phenotypic alterations in fetal immune cells by single-cell mass cytometry. Am. J. Reprod. Immunol. 2024; ... The influence of a high-fat dietary environment in the fetal period on postnatal metabolic and immune function. Obesity. 2010; ... Immunometabolism. 2024; 4 e220008 https: ... ear tag earrings
Immunometabolism in the Single-Cell Era — Research Profiles …
Witryna13 kwi 2024 · In this issue of Immunity, Levine et al. report a CyTOF-based approach for the analyses of CD8 + T cells metabolic changes at the single-cell level. This approach identified a transition state early in T cell activation that is characterized by high glycolytic and oxidative activity, providing new insight into the metabolic changes that underlie … WitrynaAdvances in high-dimensional single-cell analyses and metabolic flux have improved our understanding of immunometabolism and brought the potential to identify new therapeutic strategies for cancer (Artyomov and den Bossche, 2024; Zhou et al., 2024). How best to translate these findings remains an open question, especially given the … Witryna3 lis 2024 · Single-cell metabolomics is currently too premature for large-scale applications, and thus alternate approaches are needed for immunometabolism … ctc corrections